Article

Locating a transgene integration site by nanopore sequencing

2019-01-15

Abstract excerpt

The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven burdensome, so the genomic location of most transgenes remains unknown. To address this challenge, we applied nanopore sequencing in search of the site of integration...

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Identifiers and source

Literature Corpus work: a8f57a11-727e-5d06-aa72-31344b29bfcd
DOI: 10.1101/520627

Open publication

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