Article

Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function

2019-12-13

Abstract excerpt

Zbtb11 is a conserved transcription factor mutated in families with hereditary intellectual disability. Its precise molecular and cellular functions are currently unknown, precluding our understanding of the aetiology of this disease. Using a combination of functional genomics, genetic and biochemical approaches here we show that Zbtb11 plays essential roles in maintaining the homeostasis of mitochondrial function...

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Literature Corpus work: f78746c7-93fe-5ad7-93d0-46b59bfa3de1
DOI: 10.1101/2019.12.13.875708

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