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Article

Sulfation of Glycosaminoglycans and Its Implications in Human Health and Disorders.

Annual review of biomedical engineering - 21 Jun 2017

Soares da Costa Diana, Reis Rui L, Pashkuleva Iva

Abstract excerpt

Sulfation is a dynamic and complex posttranslational modification process. It can occur at various positions within the glycosaminoglycan (GAG) backbone and modulates extracellular signals such as cell-cell and cell-matrix interactions; different sulfation patterns have been identified for the same organs and cells during their development. Because of their high specificity in relation to function, GAG sulfation...

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PMID: 28226217
DOI: 10.1146/annurev-bioeng-071516-044610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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