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Article

N-Glycan MALDI MSI Differentiates Kidney Glomerular Disease Phenotypes.

Journal of the American Society for Mass Spectrometry - 5 Aug 2026

Angerstein Aaron O, Pasham Vishwajeeth, Kittrell Caroline, Coley Shana M, Nowling Tamara K, Drake Richard R

Abstract excerpt

Lupus nephritis (LN) and diabetic nephropathy (DN) are leading causes of kidney failure, characterized by distinct yet overlapping patterns of glomerular injury. While histopathology remains central to diagnosis, it provides limited insight into the underlying molecular remodeling. Here, we applied matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) to define the spatial N-glycan...

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PMID: 42482512
DOI: 10.1021/jasms.6c00163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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