Article

Marker genes for predicting cytokine release syndrome in vitro before CAR T cell infusion

2025-05-29

Abstract excerpt

Cytokine release syndrome (CRS) and neurotoxicity are common adverse events of the Chimeric antigen receptor (CAR) T cell therapy. Assessing the cytotoxicity associated biomarkers would be essential for therapy design to avoid developing severe toxicities. In this study, we re-analyzed previously published RNAseq results of CAR T cells before infusion and combined it with the clinical response post infusion. We ob...

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Literature Corpus work: f75d4761-6f44-58f8-bac8-c1f6f95ddfd8
DOI: 10.1101/2025.05.26.655341

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