Article

The germline/somatic DNA damage repair gene mutations modulate the therapeutic response in Chinese patients with advanced pancreatic ductal adenocarcinoma

2020-09-24

Abstract excerpt

<h4>Background: </h4> PDAC is a fatal disease with molecular heterogeneity, inducing differences in biological behavior and therapeutic strategy. NGS profiles of pathogenic alterations in Chinese PDAC population are limited. We conducted a retrospective study to investigate the predictive role of DNA damage repair (DDR) mutations in precise medicine. <h4>Methods: </h4> NGS were performed on resected tissues or per...

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Literature Corpus work: f74cdd84-d8e3-5ccf-935f-3dc28c392457
DOI: 10.21203/rs.3.rs-72325/v2

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