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The Germline/somatic DNA Damage Repair Gene Mutations Modulate the Therapeutic Response in Chinese Patients With Advanced Pancreatic Ductal Adenocarcinoma

2020-08-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> PDAC is a fatal disease with molecular heterogeneity, inducing differences in biological behavior and therapeutic strategy. NGS profiles of pathogenic alterations in Chinese PDAC population are limited. We conducted a retrospective study to investigate the predictive role of DNA damage repair (DDR) mutations in precise medicine. <bold>Methods</bold>: NGS were pe...

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Literature Corpus work
9b194082-4d7e-5205-b847-20184a992c76
DOI
10.21203/rs.3.rs-60530/v1
Open publication

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