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Characterization of the genomic landscape in large-scale Chinese patients with pancreatic cancer.

EBioMedicine - 1 Mar 2022

Zhang Xiaofei, Mao Tiebo, Zhang Bei, Xu Haiyan, Cui Jiujie, Jiao Feng, Chen Dongqin, Wang Yu, Hu Jiong, Xia Qing, Ge Weiyu, Li Shumin, Yue Ming, Ma Jingyu, Yao Jiayu, Wang Yongchao, Wang Yanling, Shentu Daiyuan, Zhang Xiao, Chen Shiqing, Bai Yuezong, Wang Yuexiang, Zhang Xuebin, Liu Qiang, Sun Yongwei, Fu Deliang, Liu Yingbin, Xiong Lei, Wang Liwei

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with an extremely poor prognosis. Effective targets for anticancer therapy confirmed in PDAC are limited. However, the characteristics of genomics have not been fully elucidated in large-scale patients with PDAC from China. METHODS: We collected both blood and tissue samples from 1080 Chinese patients with pancreatic cancer and...

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Identifiers

PMID: 35231699
DOI: 10.1016/j.ebiom.2022.103897
PMCID: PMC8886010

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