Multidimensional effects of genetic mechanisms in cancer occurrence, development and treatment.

Abstract excerpt

Cancer is a complex disease driven by progressive genetic abnormalities, with initiation, progression, and therapy response governed by multilayered genetic mechanisms. This review synthesizes key advances in cancer genetics, highlighting driver mutations, epigenetic reprogramming, non-coding RNAs, chromosomal instability, and viral integration in tumorigenesis and drug resistance. Unlike traditional reviews that...

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