Article

Efficient strategies to detect genome editing and integrity in CRISPR-Cas9 engineered ESCs

2019-05-10

Abstract excerpt

CRISPR-mediated genome engineering provides a powerful tool to study the function of genes and proteins. In the past decades, the advances in genome and transcriptome sequencing techniques have shed light on the genetic causes underlying many human diseases, such as neurodevelopmental disabilities or cancer. Sometimes, a single point-mutation in a protein coding gene has been identified as the primary cause of the...

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Literature Corpus work: f704f32a-f479-55e1-8076-f9a16a98b54b
DOI: 10.1101/635151

Open publication

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