Article

Structured clustering of the glycosphingolipid GM1 is required for membrane curvature induced by cholera toxin

2020-01-23

Abstract excerpt

<h4>ABSTRACT</h4> AB 5 bacterial toxins and polyomaviruses induce membrane curvature as a mechanism to facilitate their entry into host cells. How membrane bending is accomplished is not yet fully understood but has been linked to the simultaneous binding of the pentameric B-subunit to multiple copies of their glycosphingolipid receptors. Here, we probe the toxin membrane binding and internalization mechanisms b...

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Literature Corpus work: f6a0d8ad-0f5a-5577-ac58-c343ed8053c1
DOI: 10.1101/2020.01.22.915249

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