Article

Extraepitopic Amino Acid Substitutions Define a Change in the Accessibility of Conformational Epitopes of the Bacillus cereus HlyII C-Terminal Domain

2023-10-12

Abstract excerpt

Hemolysin II (HlyII) – one of the pathogenic factors of Bacillus cereus, a pore-forming β-barrel toxin – possesses a C-terminal extension of 94 amino acid residues, designated as the C-terminal domain of HlyII (HlyIICTD), which plays an important role in the functioning of the toxin. Our previous work described a monoclonal antibody (HlyIIC-20), capable of strain-specific inhibi-tion of hemolysis caused by HlyII,...

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Literature Corpus work: f6626ced-5fb1-5b5b-9f4c-0fb3d0129452
DOI: 10.20944/preprints202310.0759.v1

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