Article
Analysis of toxinogenic functions associated with the RTX repeat region and monoclonal antibody D12 epitope of Escherichia coli hemolysin.
Infection and immunity - 1 Feb 1994
Rowe G E, Pellett S, Welch R A
Abstract excerpt
Amino acids (aa) 550 through 850 of the Escherichia coli hemolysin (HlyA) contain sequences important for several steps in cytolysis. These include the Ca(2+)-binding glycine-rich tandem repeats recognized by the monoclonal antibody A10, the putative HlyC-dependent acylation site that corresponds to the monoclonal antibody D12 epitope, and the erythrocyte specificity domain which confers erythrolytic activity to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
