Article

A High-Homology Region in Bacterial β-Barrel Pore-Forming Toxins

2024-03-20

Abstract excerpt

Pathogenicity of many bacteria including Bacillus cereus and Staphylococcus aureus depends on pore-forming toxins (PFTs), which cause lysis of host cells by forming pores in membranes of eukaryotic cells. Bioinformatic analysis revealed in over 600 PFTs a region homologous to the Lys171-Gly250 sequence in hemolysin II (HlyII) from B. cereus, which we designated as “homologous peptide”. Three β-barrel PFTs were use...

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Literature Corpus work: 2c0a7039-42fc-5f4f-b804-825ed3124e09
DOI: 10.20944/preprints202403.1156.v1

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