Article
The role of a conserved histidine-tyrosine interhelical interaction in the ion channel domain of delta-endotoxins from Bacillus thuringiensis.
Proteins - 1 May 2006
Seale Jeffrey W
Abstract excerpt
The delta-endotoxin proteins are produced by Bacillus thuringiensis during the sporulation phase of its life cycle. These proteins exhibit insecticidal activity through receptor-mediated ion channel formation. The mode of action of these proteins requires the conversion of the protein from a water-soluble conformation to a membrane-inserted conformation. While there is X-ray structure information for the soluble...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
