Article

Gene Set Analysis for time-to-event outcome new approach based on the Generalized Berk–Jones statistic and comparison with existing methods

2021-09-08

Abstract excerpt

Gene set analysis evaluates the collective impact of groups of genes on an outcome of interest, such as disease occurrence. By incorporating biological knowledge through predefined gene sets, this approach enhances the interpretability of results and improves statistical power compared to gene-wise analyses. In the context of time-to-event data, existing methods are limited and fail to account for potentially stro...

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Literature Corpus work: f642fbc6-c01b-5764-b89a-d7aaab0f3b09
DOI: 10.1101/2021.09.07.459329

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