Article
Prospective calculation of identification power for individual genes in analyses controlling the false discovery rate.
Genetic epidemiology - 1 Dec 2012
Crager Michael R
Abstract excerpt
Recent work on prospective power and sample size calculations for analyses of high-dimension gene expression data that control the false discovery rate (FDR) focuses on the average power over all the truly nonnull hypotheses, or equivalently, the expected proportion of nonnull hypotheses rejected. Using another characterization of power, we adapt Efron's ([2007] Ann Stat 35:1351-1377) empirical Bayes approach to...
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