Article

Identification of Monotonically Classifying Pairs of Genes for Ordinal Disease Outcomes

2025-04-10

Abstract excerpt

In this study, we extend an existing classification method for identifying pairs of genes whose joint expression is associated with binary outcomes to ordinal multi-class outcomes, such as overall survival or disease progression. Our approach is motivated by the need for interpretable classifiers that can provide insights into the underlying biological mechanisms. It can be easily adapted to different research que...

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Literature Corpus work: 2ba4358a-2210-5cfe-8035-8569e4db5db7
DOI: 10.1101/2025.04.10.643941

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