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Reactivation of pre-existing T cell memory by a LADS-TT vaccine induces potent anti-tumor immunity in cervical and colon carcinoma models

2026-01-22

Abstract excerpt

<title>Abstract</title> <p> Tetanus toxoid (TT) is a highly immunogenic recall antigen that can reactivate preexisting TT-specific memory T cells. We have previously developed a <italic>Listeria</italic> -based Live Attenuated Double Substitution (LADS) vaccine platform, engineered to deliver foreign antigens, which is capable of suppressing and preventing tumor formation. In this study, we constructed several...

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Literature Corpus work
f641ba01-56dd-59a9-aefc-2346c0ddebe8
DOI
10.21203/rs.3.rs-8555643/v1
Open publication

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Reactivation of pre-existing T cell memory by a LADS-TT vaccine induces potent anti-tumor immunity in cervical and colon carcinoma modelsDOI 10.21203/rs.3.rs-8555643/v1
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