Article

How Virulence of <em>Listeria monocytogenes </em>Can Be Harnessed to Develop an Immunotherapeutic Agent

2025-11-25

Abstract excerpt

Listeria monocytogenes (Lm) is a Gram-positive, facultative intracellular bacterium traditionally known as a foodborne pathogen but increasingly recognized as a promising vector for cancer immunotherapy. Its unique virulence factors—such as listeriolysin O (LLO), internalins, phospholipases, and ActA—enable robust activation of cell-mediated immunity, making Lm-based vaccines superior to conventional treatments an...

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Literature Corpus work: f527cfea-be3c-5c13-96b4-04b0ed242f33
DOI: 10.20944/preprints202511.1895.v1

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