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mRNA-Tc-Vax vaccine induces T cell-dependent prophylactic and therapeutic protection against Trypanosoma cruzi

2025-09-16

Abstract excerpt

<title>Abstract</title> <p> Chagas disease, a globally spreading neglected disease caused by <italic>Trypanosoma cruzi</italic> , presents a major therapeutic challenge, as current treatments are largely ineffective for the chronic phase where debilitating pathology develops. Therapeutic vaccines are a promising alternative to control chronic infection and its immunopathology. Here, we developed and evaluated...

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Literature Corpus work
9d30d652-9a7a-5d22-969c-0a6f5078ea75
DOI
10.21203/rs.3.rs-7553347/v1
Open publication

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mRNA-Tc-Vax vaccine induces T cell-dependent prophylactic and therapeutic protection against Trypanosoma cruziDOI 10.21203/rs.3.rs-7553347/v1
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