Article

RUNX1A isoform is overexpressed in acute myeloid leukemia and is associated with FLT3 internal tandem duplications

2025-01-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background. </bold><italic>RUNX1A </italic>is the shortest and least expressed of the <italic>RUNX1</italic> three main isoforms (A, B, C); despite this, the leukemogenic role of its overexpression has been clearly described. Several studies have shown <italic>RUNX1A </italic>involvement in different blood cancers and pilot observations in acute leukemia have been reported. <bold>...

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Literature Corpus work: f62763b6-7fc4-5012-ae26-7de506dcb55a
DOI: 10.21203/rs.3.rs-5733882/v1

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