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Article

Distinct association of RUNX family expression with genetic alterations and clinical outcome in acute myeloid leukemia.

Cancer biomarkers : section A of Disease markers - 1 Jan 2020

Zhao Yangli, Zhang Tingjuan, Zhao Yangjing, Zhou Jingdong

Abstract excerpt

BACKGROUND: The runt-related transcription factor family (RUNXs) including RUNX1, RUNX2, and RUNX3 are key transcriptional regulators in normal hematopoiesis. RUNXs dysregulations caused by aberrant expression or mutation are frequently seen in various human cancers especially in acute myeloid leukemia (AML). OBJECTIVE: We systemically analyzed the expression of RUNXs and their relationship with...

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Source

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Identifiers

PMID: 32741803
DOI: 10.3233/CBM-200016
PMCID: PMC12662513

Genes

RUNX3
RUNX1
RUNX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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