Article

Evaluation of false positive and false negative errors in targeted next generation sequencing

2024-07-22

Abstract excerpt

<h4>Background</h4> Although next generation sequencing (NGS) has been adopted as an essential diagnostic tool in various diseases, NGS errors have been the most serious problem in clinical implementation. Especially in cancers, low level mutations have not been easy to analyze, due to the contaminating normal cells and tumor heterozygosity. <h4>Results</h4> In targeted NGS (T-NGS) analyses for reference-standar...

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Literature Corpus work: f61d8bb6-6c1a-5699-abe9-a936ad544e67
DOI: 10.1101/2024.07.22.603478

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