Article
Cracking the Code of Human Diseases Using Next-Generation Sequencing: Applications, Challenges, and Perspectives.
BioMed research international - 1 Jan 2015
Precone Vincenza, Del Monaco Valentina, Esposito Maria Valeria, De Palma Fatima Domenica Elisa, Ruocco Anna, Salvatore Francesco, D'Argenio Valeria
Abstract excerpt
Next-generation sequencing (NGS) technologies have greatly impacted on every field of molecular research mainly because they reduce costs and increase throughput of DNA sequencing. These features, together with the technology's flexibility, have opened the way to a variety of applications including the study of the molecular basis of human diseases. Several analytical approaches have been developed to selectively...
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