Article
Bioinformatics Analysis for Cell-Free Tumor DNA Sequencing Data.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Chen Shifu, Liu Ming, Zhou Yanqing
Abstract excerpt
As a major biomarker of liquid biopsy, cell-free tumor DNA (ctDNA), which can be extracted from blood, urine, or other circulating liquids, is able to provide comprehensive genetic information of tumor and better overcome the tumor heterogeneity problem comparing to tissue biopsy. Developed in recent years, next-generation sequencing (NGS) is a widely used technology for analyzing ctDNA. Although the technologies...
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