Article

Anaphylatoxin Receptor C3AR1 Promotesoptic Nerve Degeneration in DBA/2J Mice

2020-07-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>The risk of glaucoma increases significantly with age and exposure to elevated intraocular pressure, two factors linked with neuroinflammation. The complement cascade is a complex immune process with many bioactive end-products, including mediators of inflammation called anaphylatoxins. Complement cascade activation has been shown in glaucoma patients and models o...

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Literature Corpus work: f5f57ee3-c326-573a-8c7a-aabcf0bf947e
DOI: 10.21203/rs.3.rs-39367/v1

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