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Article

Microarray Analysis of Retinal Gene Expression in the DBA/2J Model of Glaucoma

27 Feb 2006

Abstract excerpt

PURPOSE: The DBA/2J mouse is a model for secondary angle-closure glaucoma, due to iris atrophy and pigment dispersion, which ultimately lead to increased intraocular pressure (IOP). The study was undertaken to correlate changes in retinal gene expression with IOP elevation by performing microarray analysis of retinal RNA from DBA/2J mice at 3 months before disease onset and at 8 months after IOP elevation....

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Identifiers

PMID: 16505032
DOI: 10.1167/iovs.05-0865

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