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Elucidating the Multi-Target Mechanisms of Niclosamide in Hepatocellular Carcinoma through Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations

2026-04-01

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<title>Abstract</title> <p> The Hepatocellular carcinoma (HCC) continues to be a major contributor to cancer-related deaths globally, fueled by intricate molecular diversity and widespread resistance to existing targeted treatments. Drug repurposing provides a strategy that is both effective and economical for identifying new therapeutic options. Niclosamide (NIC), which is approved by the food drug administrati...

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Literature Corpus work
f5f42a70-9c39-5d99-836b-2cc63bfed540
DOI
10.21203/rs.3.rs-9148243/v1
Open publication

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