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A Systems Biology and Generative Artificial Intelligence Framework for Rational Multi-Target Drug Design in Metabolic Dysfunction-Associated Steatotic Liver Disease: Proof-of-Concept Identification of HPM-001

2026-08-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction:</bold> Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading cause of chronic liver disease worldwide and is characterized by complex interactions among metabolic, inflammatory, and fibrogenic pathways. Current pharmacological strategies predominantly target single molecular mechanisms, limiting their ability to address the multifactorial...

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Literature Corpus work
3b5b40f4-d061-5f8a-9b6f-9269fcd1013a
DOI
10.21203/rs.3.rs-10620781/v1
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A Systems Biology and Generative Artificial Intelligence Framework for Rational Multi-Target Drug Design in Metabolic Dysfunction-Associated Steatotic Liver Disease: Proof-of-Concept Identification of HPM-001DOI 10.21203/rs.3.rs-10620781/v1
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