Back to search

Article

In-silico Identification of Potential Therapeutic Targets against Virus Induced Hepatocellular Carcinoma

2026-01-06

Abstract excerpt

<title>Abstract</title> <p> Background Chemo resistance in hepatocellular carcinoma is a challenge that leads to a high mortality rate. The discovery of novel drugs and drug targets is crucial to develop combination therapy. The study reports drug targets based on an ‘omics’-based approach and studied <italic>in silico</italic> binding of bufalin compound to potential drug target. Method Gene expression data...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8a0979c2-48da-57d9-9088-b00628db3285
DOI
10.21203/rs.3.rs-8468854/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
In-silico Identification of Potential Therapeutic Targets against Virus Induced Hepatocellular CarcinomaDOI 10.21203/rs.3.rs-8468854/v1
Integrative in-silico analysis on phytocompounds of Pajanelia longifolia against hepatocellular carcinoma: gene network target identification, molecular docking, simulation and ADMET profilingSemantic proximity
Screening of HRas, RRas and FOS as Potential Pharmacodynamic Candidates for the Treatment of Hepatocellular CarcinomaSemantic proximity
The mechanism of CPT1A involved in hepatocellular carcinoma growth and Bufalin regulates malignant behavior of hepatocellular carcinoma via CPT1ASemantic proximity
Identification of Hub Genes and CDK1-Targeting Therapeutics in Hepatocellular Carcinoma: Bioinformatics and Simulation StudySemantic proximity
Identification of hub genes and potential drugs in hepatocellular carcinoma through integrated bioinformatics analysisSemantic proximity
Decoding the mechanism of andrographolide to combat hepatocellular carcinoma: a network pharmacology integrated molecular docking and dynamics approachSemantic proximity
Transcriptomic Insights into the Antitumor Mechanism of Bufalin in Hepatocellular Carcinoma Cell HepG2Semantic proximity
Integrated transcriptomic analyses identifies host-targeting repurposing drugs for hepatitis C virus infection and related hepatocellular carcinomaSemantic proximity
Integrative analysis of the molecular signature of target genes involved in the antitumor effects of cantharidin on hepatocellular carcinomaSemantic proximity
Elucidating the Multi-Target Mechanisms of Niclosamide in Hepatocellular Carcinoma through Network Pharmacology, Molecular Docking, and Molecular Dynamics SimulationsSemantic proximity
Target prediction and potential application of dihydroartemisin on hepatocarcinomaSemantic proximity
Identification of a chromatin regulator signature and potential candidate drugs for hepatocellular carcinomaSemantic proximity
Select a neighboring publication to make it the new centre.