Article

Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system

2021-06-07

Abstract excerpt

Respiratory diseases including influenza A virus (IAV) infections represent a major threat to human health. While the development of a vaccine requires a lot of time, a fast countermeasure could be the use of defective interfering particles (DIPs) for antiviral therapy. IAV DIPs are usually characterized by a large internal deletion in one viral RNA segment. Consequentially, DIPs can only propagate in presence of...

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Literature Corpus work: f5efc7d7-9505-56f1-bac8-82d206ee190d
DOI: 10.1101/2021.06.07.446880

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