Article

Age-dependent Non-silent Somatic Mutation with Transcriptomic Landscape and Prognosis of Lower Grade Glioma

2021-02-23

Abstract excerpt

Glioma accounts for 80% of all malignant brain tumors and is the most common adult primary brain tumor. Age is an important factor affecting the development of cancer as somatic mutations accumulate with age. In this study, we aimed to analyze the significance of age-related non-silent somatic mutations in glioma prognosis. Histological tumor grade depends on age at diagnosis in patients with IDH1, TP53, ATRX, and...

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Literature Corpus work: f5e9c9e0-90ee-5211-a3d2-dffedbc1d88c
DOI: 10.20944/preprints202102.0501.v1

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