Article

Defining the Antigenic Topology and Prospective Binding Breadth of Vaccination-induced SARS-CoV-2 Neutralizing Antibodies

2026-03-04

Abstract excerpt

Antibodies that neutralize SARS-CoV-2 primarily target the viral spike glycoprotein, yet the breadth of these responses is continually challenged by viral evolution. While extensive structural studies have defined epitopes across the spike protein, how antibodies elicited by the initial mRNA vaccination campaigns perform against subsequently emerging variants remains an important question. Here, we structurally an...

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Literature Corpus work: f5d1ef0c-052c-591b-b3d2-d474015886d0
DOI: 10.64898/2026.03.03.709398

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