Article

Spatially resolved diversity in molecular states underlies congenital melanocytic nevi and associated tumors

2026-01-21

Abstract excerpt

The congenital melanocytic nevus (CMN) is a developmental skin disorder characterized by prenatal melanocyte overgrowth, exhibiting heterogeneity in surface size, depth, and clinical behavior. Large/giant CMN carry an elevated, anticipatory melanoma risk relative to more common, small CMN. However, deeper insights into melanocytic states, genomic and epigenomic alterations, and microenvironmental cues governing di...

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Literature Corpus work: 4c61a8a9-dcb5-53a2-baf8-3e8c3ade932d
DOI: 10.64898/2026.01.20.700607

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