Molecular pathology as a diagnostic aid in difficult-to-classify melanocytic tumours with spitzoid morphology.

doi:10.1016/j.ejca.2021.02.025

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Article

Molecular pathology as a diagnostic aid in difficult-to-classify melanocytic tumours with spitzoid morphology.

European journal of cancer (Oxford, England : 1990) - 1 May 2021

Zaremba Anne, Lodde Georg, Murali Rajmohan, Philip Manuel, Cosgarea Ioana, Jansen Philipp, Chorti Eleftheria, Rose Christian, Hemmerlein Bernhard, Matull Johanna, Thielmann Carl M, Kretz Julia, Möller Inga, Sucker Antje, Paschen Annette, Livingstone Elisabeth, Zimmer Lisa, Horn Susanne, Schadendorf Dirk, Hadaschik Eva, Griewank Klaus

Abstract excerpt

Accurate classification of melanocytic proliferations has important implications for prognostic prediction, treatment and follow-up. Although most melanocytic proliferations can be accurately classified using clinical and pathological criteria, classification (specifically distinction between nevus and melanoma) can be challenging in a subset of cases, including those with spitzoid morphology. Genetic studies...

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Identifiers

PMID: 33773277
DOI: 10.1016/j.ejca.2021.02.025
PMCID: PMC8087654

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