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Article

New insights into the aetiology of colorectal cancer from genome-wide association studies.

Nature reviews. Genetics - 1 Jun 2009

Tenesa Albert, Dunlop Malcolm G

Abstract excerpt

Genome-wide association studies have recently identified ten common genetic variants associated with colorectal cancer susceptibility, several suggesting the involvement of components of the transforming growth factor beta (TGFbeta) superfamily signalling pathway. To date, no causal sequence variants have been identified, and risk seems to be mediated through effects on gene regulation. Several markers are...

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PMID: 19434079
DOI: 10.1038/nrg2574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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