Article

The cell cycle state defines TACC3 as a regulator gene in glioblastoma

2020-10-20

Abstract excerpt

Overexpression and mitosis-promoting roles of Transforming acidic coiled-coil containing protein 3 (TACC3) are well-established in many cancers, including glioblastoma (GBM). However, the effector gene networks downstream of TACC3 remain poorly defined, partly due to an incomplete understanding of TACC3 cell lineage specificity and its dynamic role during the cell cycle. Here, we use a patient-derived GBM model to...

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Literature Corpus work: f58b1411-f0bd-513b-9f2e-474939d1fa81
DOI: 10.1101/2020.10.20.346643

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