Article

Single-workflow Nanopore whole genome sequencing with adaptive sampling for accelerated and comprehensive pediatric cancer profiling

2025-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Timely and comprehensive molecular classification is critical for therapeutic decisions in pediatric oncology. However, current diagnostic workflows rely on multi-step testing and are resource- and time-intensive. We present whole-genome sequencing with adaptive sampling (AS-WGS) protocol using Oxford Nanopore Technologies optimized for pediatric oncology, enabling unified detection of genomic,...

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Literature Corpus work: f56241f2-769c-5a01-a302-6550f7ca5728
DOI: 10.1101/2025.10.02.25336569

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