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Benefits for children with suspected cancer from routine whole-genome sequencing

1 Jul 2024

Abstract excerpt

Clinical whole-genome sequencing (WGS) has been shown to deliver potential benefits to children with cancer and to alter treatment in high-risk patient groups. It remains unknown whether offering WGS to every child with suspected cancer can change patient management. We collected WGS variant calls and clinical and diagnostic information from 281 children (282 tumors) across two English units (n = 152 from a...

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PMID: 38956197
DOI: 10.1038/s41591-024-03056-w

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