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Real-time genomic characterization of pediatric acute leukemia using adaptive sampling

24 Mar 2025

Abstract excerpt

Effective treatment of pediatric acute leukemia is dependent on accurate genomic classification, typically derived from a combination of multiple time-consuming and costly techniques such as flow cytometry, fluorescence in situ hybridization (FISH), karyotype analysis, targeted PCR, and microarrays [1-3]. We investigated the feasibility of a comprehensive single-assay classification approach using long-read...

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PMID: 40128561
DOI: 10.1038/s41375-025-02565-y

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