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Metabolic Control of Germline Formation and Differentiation in Mammals

1 Jan 2022

Abstract excerpt

BACKGROUND: The germ cell lineage involves dynamic epigenetic changes during its formation and differentiation that are completely different from those of the somatic cell lineage. Metabolites and metabolic pathways have been reported as key factors related to the regulation of epigenetics as cofactors and substrates. However, our knowledge about the metabolic characteristics of germ cells, especially during the...

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PMID: 35086109
DOI: 10.1159/000520662

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