Back to search

Article

Parent-child signals identify candidate cancer driver genes

2021-02-03

Abstract excerpt

<h4>Background: </h4> The DREAM Challenge evaluated methods to identify molecular pathways facilitating the detection of multiple genes affecting critical interactions and processes. Dysregulation of pathways by well-known driver genes is often found in the development and progression of cancer. We used the gene interaction networks provided and the scoring rounds to test disease module identification methods to n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f549d70a-16ab-5238-b99e-ab38a31cf125
DOI
10.12688/f1000research.22391.1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Parent-child signals identify candidate cancer driver genesDOI 10.12688/f1000research.22391.1
Select a neighboring publication to make it the new centre.