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Single-cell transcriptomics reveals inter-ethnic variation in immune response to Falciparum malaria

18 Feb 2025

Abstract excerpt

Africa's environmental, cultural, and genetic diversity can profoundly shape population responses to infectious diseases, including malaria caused by Plasmodium falciparum. Differences in malaria susceptibility among populations are documented, but the underlying mechanisms remain poorly understood. Notably, the Fulani ethnic group in Africa is less susceptible to malaria compared to other sympatric groups, such...

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PMID: 39970911
DOI: 10.1016/j.ajhg.2025.01.020

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