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Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes

14 Oct 2022

Abstract excerpt

Abstract Listeria monocytogenes is a foodborne intracellular bacterial pathogen leading to human listeriosis. Despite a high mortality rate and increasing antibiotic resistance no clinically approved vaccine against Listeria is available. Attenuated Listeria strains offer protection and are tested as antitumor vaccine vectors, but would benefit from a better knowledge on immunodominant vector antigens. To...

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PMID: 36241641
DOI: 10.1038/s41467-022-33721-y

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