Article
A mutant in the Listeria monocytogenes Fur-regulated virulence locus (frvA) induces cellular immunity and confers protection against listeriosis in mice.
Journal of medical microbiology - 1 Feb 2013
McLaughlin Heather P, Bahey-El-Din Mohammed, Casey Pat G, Hill Colin, Gahan Cormac G M
Abstract excerpt
Listeria monocytogenes is a Gram-positive intracellular pathogen that is responsible for listeriosis, a potentially fatal, food-borne illness. Due to its cytoplasmic location during infection, this pathogen can mediate a long-lasting cellular immune response, which makes attenuated strains strong candidates for vaccine development. Recently, our group identified and characterized frvA (Fur-regulated virulence...
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