Article

The unique properties of Big tau in the visual system

2023-07-12

Abstract excerpt

Tau is a microtubule associated protein that plays important roles in regulating the properties of microtubules and axonal transport, as well as tauopathies associated with toxic aggregates leading to neurodegenerative diseases. It is encoded by the MAPT gene forming multiple isoforms by alternative splicing of exons 2/3 at the N-terminal and exon 10 which determines the numbers of microtubule binding repeats (3R...

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Literature Corpus work: f51c8149-16b2-5fb8-81a9-f907fbe37b5a
DOI: 10.1101/2023.07.11.548562

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