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Tau; One Protein, So Many Diseases

3 Feb 2023

Abstract excerpt

Tau, a member of the microtubule-associated proteins, is a known component of the neuronal cytoskeleton; however, in the brain tissue, it is involved in other vital functions beyond maintaining the cellular architecture. The pathologic tau forms aggregates inside the neurons and ultimately forms the neurofibrillary tangles. Intracellular and extracellular accumulation of different tau isoforms, including dimers,...

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PMID: 36829521
DOI: 10.3390/biology12020244

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