Back to search

Article

The impact of sex, age, and genetic ancestry on DNA methylation across tissues

2025-05-03

Abstract excerpt

<h4>ABSTRACT</h4> Understanding the consequences of individual DNA methylation variation is crucial for advancing our knowledge of human biology and disease. Yet, the collective impact of individual traits on DNA methylation and their downstream effects on gene expression across human tissues remain poorly understood. Here, we quantify the contributions of sex, age, genetic ancestry, and BMI on autosomal DNA meth...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f519ce53-798d-51da-9379-bfd2bc42d77c
DOI
10.1101/2025.04.29.651179
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The impact of sex, age, and genetic ancestry on DNA methylation across tissuesDOI 10.1101/2025.04.29.651179
Genetic and environmental influences interact with age and sex in shaping the human methylome.Semantic proximity
Population epigenetics: deciphering DNA methylation diversity and its implications for health, disease, and evolution.Semantic proximity
Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposuresSemantic proximity
Human body epigenome maps reveal noncanonical DNA methylation variation.Semantic proximity
A comprehensive map of the ageing blood methylomeSemantic proximity
A comprehensive map of the ageing blood methylomeSemantic proximity
Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome.Semantic proximity
Human panepigenome represents epigenomic diversitySemantic proximity
Genome-wide mapping of sex-associated autosomal DNA methylation in major blood cell typesSemantic proximity
Cross-tissue patterns of DNA hypomethylation reveal genetically distinct histories of cell developmentSemantic proximity
Systemic interindividual epigenetic variants link periconceptional environment to human fetal developmentSemantic proximity
Tissue-specific divergence in sex-biased DNA methylation across the lifespanSemantic proximity
Select a neighboring publication to make it the new centre.