Article

Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors

2023-12-19

Abstract excerpt

<h4>ABSTRACT</h4> The spread of cancer from organ to organ (metastasis) is responsible for the vast majority of cancer deaths; however, most current anti-cancer drugs are designed to arrest or reverse tumor growth without directly addressing disease spread. It was recently discovered that tumor cell-secreted interleukin-6 (IL-6) and interleukin-8 (IL-8) synergize to enhance cancer metastasis in a cell-density dep...

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Literature Corpus work: f511cbbc-bca2-5faa-b5ae-8d4b0986d5e1
DOI: 10.1101/2023.12.18.570445

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